Corsi precongressuali - 17° Congresso Nazionale ICAR, Padova...

Corsi precongressuali

I 4 Corsi Precongressuali ICAR 2025 si svolgeranno in contemporanea mercoledì 21 maggio dalle ore 15.00 alle ore 17.30.

The availability of antiretroviral therapies characterized by high efficacy and safety has completely changed the prognosis of HIV infection, allowing good immunological recovery for patients with HIV. Nevertheless, due to the high rate of patients receiving a late-stage diagnosis, the proportion of those presenting with opportunistic diseases, either concurrently with or following diagnosis, has increased over the years. This pre-congress course aims to explore the state of the art regarding opportunistic infections and HIV-related diseases from both an epidemiological and clinical perspective and to provide updated guidelines on diagnosis, treatment, and prophylaxis for these conditions.

15.00-15.30

Opportunistic Infections from 1981 to today: has something changed? A. Vergori, Roma

15.30-16.00

Updates in the clinical management and prophylaxis of Opportunistic Infections G. Bozzi, Milano

16.00-16.30

The Changing Face of HIV-Associated Malignancies: Advances, Opportunities, and Future Directions E. Vaccher, Aviano PN

16.30-17.00

Vaccination in HIV-infected adults could help us to prevent Opportunistic Infections? F.M. Fusco, Napoli

17.00-17.30

Discussion

As long-term management of people with HIV (PWH) evolves, direct contact with healthcare providers becomes less frequent, risking the neglect of important aspects of the individual's life. Patient-Reported Outcomes (PROs) can bridge these gaps, providing a proactive tool to monitor the quality of life and well-being of PLWH. The spread of apps facilitates the use of PROs in clinical practice, turning them into a communication channel that can signal critical issues in real time. This course aims to stimulate a debate to explore how PROs can become increasingly effective, if possible to enhance continuity of care and the centrality of the individual in their healthcare journey.

15.00-15.20

Understanding patient-centered care: an introduction to PROs, PROMs e QoL A. Cingolani, Roma

15.20-15.35

The use of PROs in clinical research: the experience of ICONA Project A. Tavelli, Milano

15.35-15.50

PROs at service of PLWH. The use of Multiface App as an intervention tool F. Benedetta, Brescia

15.50-16.05

PROs in real life: clinical cases and implications for practice J. Milic, Modena

16.05-16.35

Back to the patient: from the current point of view to the role of the community G.V. Calvino, Roma – V.L. del Negro, Roma

16.35-17.30

Discussion

In Italy, about 90% of people living with HIV (PWH) on treatment have a suppressed viral load. However, highly treatment-experienced (HTE) PWH, who represent 1-10% of all PWH, are at higher risk of virological failure and clinical progression. In addition, HTE PWH often require complex regimens with multiple drugs and multiple routes of administration, increasing the risk of drug interactions and adverse events. Prolonged ART exposure leads to accumulated toxicities and, in combination with ageing and inflammation, increases the risk of metabolic and oncological comorbidities. This course will review strategies for optimising ART in this population, focusing on the role of resistance testing in guiding treatment decisions. It will also discuss the role of new drugs with novel mechanisms of action that offer promising solutions to overcome resistance and simplify regimens for this challenging population.

15.00-15.20

Clinical challenges of HTE - How I Manage MDR-HIV R. Gagliardini, Roma

15.20-15.40

Diagnostic/virological challenges of HTE – Insight on drug resistance to antiretrovirals from new drug classes F. Saladini, Siena

15.40-16.00

Current and future perspectives in HIV drug resistance monitoring N. Clementi, Milano

16.00-16.20

Suppressed HTE-MDR PWH: a plunge in the HIV-DNA reservoir F. Lombardi, Roma

16.20-16.40

Clinical case - How would you manage HIV-MDR? An interactive clinical case M. Mazzitelli, Padova

16.40-17.30

Discussion

The rapid evolution of HIV research requires a solid understanding of advanced statistical methods to interpret complex data accurately. This pre-conference workshop is designed to deepen researchers’ understanding of advanced statistical methods and how they can be applied to drive more robust HIV studies. Through expert-led discussions, attendees will explore the principles of causality, strategies to mitigate bias in observational studies, the risks embedded in clinical trials, and the synthesis of evidence through meta-analyses and systematic reviews. Participants will gain practical insights to elevate their research design and data interpretation, enabling them to make more informed and impactful contributions to the HIV research landscape.

15.00-15.25

Causality or Association? Decoding the Links in HIV Research A. Cozzi-Lepri, London UK

15.25-15.35

Discussion

15.35-16.00

Bias Beware: Strengthening Observational Studies with the Trial Emulation Strategy A. Giacomelli, Milano

16.00-16.10

Discussion

16.10-16.35

All that glitters is not gold: the Hidden Risks in HIV Clinical Trials A. Cervo, Modena

16.35-16.45

Discussion

16.45-17.10

Meta-Analyses and Systematic Reviews: Synthesizing Evidence for Stronger HIV Research M. Cinquini, Milano

17.10-17.20

Discussion

17.20-17.30

Final Considerations A. Borghetti, Pisa – A. De Vito, Sassari

Promosso da
SIMIT - Società Italiana di Malattie Infettive e Tropicali

e da

INMI, Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani IRCCS

ISS, Istituto Superiore di Sanità

AMCLI, Associazione Microbiologi Clinici Italiani

SIICA, Società Italiana di Immunologia, Immunologia Clinica e Allergologia

SIMaST, Società Interdisciplinare per lo Studio delle Malattie Sessualmente Trasmissibili

SITA, Società Italiana per la Terapia Antinfettiva Antibatterica Antivirale Antifungina

SIV-ISV, Società Italiana di Virologia - Italian Society for Virology

ANLAIDS, Associazione Nazionale per la Lotta contro l’AIDS ETS

ARCIGAY, Associazione LGBTQIA+ Italiana APS

ARCOBALENO Aids ODV

ASA, Associazione Solidarietà AIDS-ODV

C.I.C.A., Coordinamento Italiano delle case alloggio per persone con HIV/AIDS ETS

EpaC, Associazione EpaC ETS

LILA, Lega Italiana per la Lotta contro l’AIDS Onlus

Mario Mieli, Circolo Cultura Omosessuale Mario Mieli APS

Milano Check Point, Associazione Milano Checkpoint ETS

NADIR, Associazione Nadir ETS

NPS Italia, Network Persone Sieropositive APS

PLUS, Rete persone LGBT+ sieropositive APS

Corsi precongressuali - 17° Congresso Nazionale ICAR, Padova...

I 4 Corsi precongressuali in programma ad ICAR 2025 che si...